Federal investigators from the National Transportation Safety Board launched an inquiry into the runway overrun of an Amazon cargo plane at Miami International Airport on Sunday, September 6, 2026. The Boeing 767-300, operating as Prime Air Flight 7598 for Amazon by 21 Air, arrived from San Juan, Puerto Rico, and overran the runway around 2 p.m. Eastern Time.

The aircraft struck vehicles beyond the runway, caught fire, and came to rest off the pavement. Miami-Dade officials reported five people killed and five injured. Three of the injured were listed in critical condition. Some victims were trapped in vehicles and required extrication. The pilot and co-pilot were also trapped in the aircraft for a period. Approximately 200 firefighters and more than 60 apparatus responded.

The plane was traveling at approximately 112 knots when it left the usable runway, according to flight-tracking data. Thunderstorms and wind gusts up to 30 mph were present in the area at the time. The cause remains under investigation. The NTSB deployed a go-team and planned a news conference for Monday.

Airport operations were disrupted, with numerous flights canceled or delayed. Two of four runways reopened later Sunday. 21 Air and Amazon issued statements expressing condolences and pledging cooperation with the investigation. Identities of those killed had not been publicly released as of early Monday.

The Miami crash remains the focus of active federal and local response. Further details are expected as the cargo plane investigation proceeds.

SOURCES
Associated Press, CNN, BBC, Miami-Dade County officials statements, NTSB announcement, FAA.